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VITAMIN D KIDNEY STONES

VITAMIN D KIDNEY STONES

Farmazon CZ янв 14, 2022 Main 0 Comments

IS IT POSSIBLE TO DRINK VITAMIN D WITH ICD, DOES VITAMIN D PROVOKE KIDNEY STONES?

Let's figure it out:

To do this, you need to touch on calcium metabolism in the body, its violation is one of the risk factors for the occurrence and recurrence
urolithiasis (ICD)

Calcium metabolism involves parathyroid hormone, vitamin D and calcitonin.

We are interested in vitamin D.

In the regulation of calcium metabolism, one of its tasks is to increase the rate of calcium absorption in the gastrointestinal tract.

Therefore, theoretically, when there is a lot of vitamin D, there is also a lot of calcium and calcium rises in the blood (hypercalcemia) and appears in the urine (hypercalciuria)

A safe level of vitamin D, which does not lead to an increase in calcium either in the blood or in the urine, is considered to be 150 ng / ml. If you remember the reference values, then there the upper limit is 100 ng / ml. Thus, even approaching the upper threshold, we have a certain safe margin.

I will say in advance that it is precisely because of this property - an increase in calcium absorption in the gastrointestinal tract, that vitamin D was "accused", and in some works is still "accused" of the formation or recurrence of stone formation.

To what extent is vitamin D involved in the formation and recurrence of KSD?

There are many works for and against.

I would like to emphasize that the appearance of calcium in the urine (and therefore its increased excretion) is indeed one of the mechanisms for the formation of stones, but besides this there are many other factors (oxalates, uric acid salts, increased acidity of urine, a decrease in volume, and so on)

In addition, an increase in calcium absorption in the gastrointestinal tract may not be due to vitamin D, but, for example, due to a genetic factor.

At the moment, reviewing all possible studies, the conclusion is the following:

If you do not have kidney stones, vitamin D deficiency needs to be replenished. It is safe and cannot lead to ICD.

If you already have KSD, then there is no definite answer on how vitamin D affects the same recurrence, but to a greater extent, the authors tend to believe that vitamin D is safe. Definitely - vitamin D deficiency in ICD must be replenished *under laboratory control.

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